The advantages and disadvantages of painless gastroenteroscopy are that it enhances the patient’s comfort during the examination and facilitates the operator’s delicate operation; at the same time, it brings certain risks to the patient. Painless gastroenteroscopy is a gastroenteroscopy performed on a patient under anesthesia. During ordinary gastrointestinal examination, as the patient is in the awake state, the operator is prone to bring abdominal pain, abdominal distension, nausea, choking sensation and other discomforts to the patient when operating gastrointestinal microscopy. It gives the patient a strong feeling of fear and other discomfort. The advantages and disadvantages of painless gastroenteroscopy are as follows: 1. Advantages: painless gastroenteroscopy greatly reduces the patient’s physical pain and psychological fear, and at the same time, it is very conducive to the operator’s examination operation. 2. Disadvantages: However, painless gastroenteroscopy has corresponding risks. Because of the need for intravenous anesthesia, the risk of anesthesia accidents may occur, such as respiratory safety during anesthesia, wakefulness after anesthesia, aspiration and other situations, as well as the operation of the examination with the problem, and so on. When doing painless gastroscopy, it is necessary to strictly grasp the indications and master the indications of the examination.