Pubic sores may be caused by folliculitis, condyloma acuminatum, syphilis, etc. They can usually be treated with erythromycin, interferon as well as penicillin. 1. Folliculitis: due to the patient does not pay attention to hygiene, resulting in pubic hair follicle blockage, the formation of folliculitis, may appear local redness and swelling. Generally, you can disinfect it by rubbing iodophor and so on externally, and use erythromycin to treat it after disinfection, which can make the condition improved. 2. Condyloma acuminatum: After the patient is infected with HPV, there will be cauliflower-like or papilla-like superfluous organisms, which are very easy to break and bleed, and after ulceration, they can be manifested as pubic long sores. It can be treated with interferon suppositories and other antiviral drugs, and also requires frequent review and treatment under the guidance of a doctor. 3. Syphilis: caused by syphilis spirochete infection, pubic sores are commonly found in the first stage of syphilis, manifested as a single, painless, itchless, round or oval, clearly defined ulcerated surface. Penicillins are the drugs of choice for syphilis, such as benzylpenicillin, procaine aqueous penicillin G, and so on. Treatment of long sores in the pubic area may be other methods, any of which should be done on the advice of a doctor. If any significant discomfort occurs, you should immediately go to a specialized hospital for effective treatment.