There is no fixed time and clear regulation on how often it is appropriate to review CA125, patients can choose according to their own situation, for example, if CA125 is found to be mildly elevated in physical examination, and no other abnormality is detected, it can be reviewed once in 3~6 months, and if CA125 is high in tumor treatment, it can be reviewed once in 1~2 months. CA125 is one kind of tumor marker, which can be seen in lung cancer, breast cancer, ovarian cancer and other tumors, and also can be seen in hepatitis, pelvic inflammatory disease and pregnant women. The elevation of CA125 in oncological diseases is often greater than that in non-oncological diseases, and it is generally believed that the higher the elevation, the greater the relationship with oncological diseases. If CA125 is found to be mildly elevated during physical examination and no other abnormality is found, it can be reviewed and compared in 3~6 months. If the patient has been diagnosed with malignant tumor, and CA125 is high or continues to be elevated during treatment, it can be reviewed in 1~2 months to help determine whether the treatment is effective or not, and the tumor markers will generally decrease when the treatment is effective. In addition to the above, high CA125 can also be reviewed once a year with a routine physical examination if it is determined to be related to a benign disease. Usually, there is no fixed time and clear regulations on how often it is appropriate to review CA125, so it is recommended that patients should consult the hospital in time, and choose the appropriate time for review under the guidance of the doctor.