The incidence of cerebral infarction is increasing and the disability and mortality rates are increasing year by year due to the rising economic level and aging population. If the correct treatment is given quickly during the acute phase of cerebral infarction, it will greatly improve the prognosis of patients. For sudden onset, such as confusion, weakness of limbs, inability to speak, and blurred vision, one must be highly alert to acute cerebral infarction. As soon as they are detected, they should be sent to the doctor immediately. If intravenous thrombolytic drug treatment is obtained within 4.5 hours, it is possible to release the embolism and restore oxygen and blood supply before complete infarction of brain cells occurs. If beyond 4.5 hours and within 8 hours, there is an opportunity to try arterial thrombolysis or mechanical embolization. Transarterial thrombolysis is the direct insertion of a microcatheter into the thrombus through the arterial vessel to inject thrombolytic drugs, which can significantly increase the concentration of local thrombolytic drugs, increase the contact area of drugs with the embolus, and reduce the total amount of drugs used. At the same time, a microguide wire can be used to mechanically break the embolus and accelerate the rate of thrombus dissolution, and an intracranial stent can also be placed at the same time. This technique has a high rate of recanalization of occluded vessels and can restore blood circulation in the ischemic area at an early stage, followed by good clinical efficacy. Compared with intravenous thrombolysis, it can effectively reduce side effects such as systemic bleeding and shorten the thrombolysis time and increase the recanalization rate of occluded vessels, and is suitable for acute cerebral infarction patients with onset time of 8 hours or less in the internal carotid artery system and 12 hours in the vertebrobasilar artery system. Arterial thrombolysis is a powerful supplement to intravenous thrombolysis, and its timely administration within the time window can greatly improve the recanalization rate of cerebral infarction patients and reduce the disability and mortality of cerebral infarction patients. If patients with suspected acute cerebral infarction are found, they should go to an experienced and qualified hospital as soon as possible.