Many people with Parkinson’s disease or their family members are often confused about the difference between Parkinson’s syndrome and Parkinson’s disease when they access treatment and prevention information on the Internet, thinking that they are both the same disease. In fact, Parkinson’s disease ≠ Parkinson’s syndrome. Hospital neurosurgery Professor Wang pointed out that what is usually called Parkinson’s syndrome and primary Parkinson’s disease are not the same thing. A, Parkinson’s syndrome and Parkinson’s disease is the same Parkinson’s disease and Parkinson’s syndrome, looks just the difference between the disease and the syndrome, but in fact is very different. In terms of pathogenesis, Parkinson’s disease is a decrease in dopamine neurons in the substantia nigra of the midbrain, resulting in a deficiency of dopamine in the substantia nigra and striatum, while Parkinson’s syndrome is caused by abnormalities in the extravertebral system of the motor regulatory system due to infection, trauma, hemorrhage, infarction, etc. Therefore, the syndrome is a group of syndromes (clinical manifestations) rather than a separate disease. The most common type is Parkinson’s disease (about 80%), also known as “primary Parkinson’s disease” or “idiopathic Parkinson’s disease”. We are generally accustomed to say Parkinson’s disease is primary Parkinson’s disease. In a narrow sense, Parkinson’s syndrome refers to a group of diseases that have similar signs and symptoms to Parkinson’s disease caused by various causes, in addition to Parkinson’s disease, which can be divided into secondary Parkinson’s syndrome, Parkinson’s superimposed syndrome and genetic degenerative Parkinson’s syndrome. Generally Parkinson’s syndrome develops more rapidly than Parkinson’s disease. Parkinson’s syndrome is divided into the following four categories: 1, Parkinson’s disease 2, secondary Parkinson’s syndrome: refers to trauma, poisoning, drugs, cerebrovascular disease, tumors, encephalitis and other causes of Parkinson’s syndrome 3, genetic degenerative Parkinson’s syndrome 4, Parkinson’s superposition syndrome 3, Parkinson’s disease and Parkinson’s syndrome treatment is the same “treatment is preceded by diagnosis, after detailed Asking the patient’s medical history, observing the symptoms exhibited by the patient, the disease progression status, the test of limb flexibility, some patients also need to do some tests, such as brain MRI images, to observe the structural changes in the brain, to help distinguish Parkinson’s disease from secondary Parkinson’s disease, Parkinson’s superposition syndrome, etc.” After diagnosis comes treatment. Generally, patients with primary Parkinson’s disease take medications such as Medopa, Antan, and Morphol, which are effective in controlling symptoms and slow progression of the disease. Secondary Parkinson’s disease or Parkinson’s disease superimposed syndrome, on the other hand, progresses more quickly and can also take medications such as Medopa, but the results may not be as good as those for primary Parkinson’s disease. Regarding the treatment of brain pacemaker surgery, the first diagnosis is primary Parkinson’s disease, the age is usually under 75 years old, and the age can be extended if the physical condition is good, and the disease duration is more than 4 years, after a detailed preoperative evaluation to decide whether the surgery can be performed.