The difference between orchitis and testicular cancer: 1. In terms of the nature of the disease, orchitis is a benign disease, which is completely curable. On the other hand, testicular cancer is a malignant tumor, which cannot be completely cured and can only achieve clinical remission. 2. In terms of symptoms, orchitis mainly manifests as acute swelling and pain in the testicles, and may be accompanied by changes such as local skin temperature increase, scrotal redness and swelling or body temperature increase. Testicular cancer, on the other hand, usually does not have acute swelling and pain, and the degree of pain is less than that of orchitis, and does not have redness and swelling of scrotal skin or elevated body temperature, etc. In terms of treatment, orchitis needs to be treated conservatively with drugs, and can be cured by anti-infection treatment with sensitive antibiotics. Testicular cancer, on the other hand, requires surgery, which requires removal of all testicles on one side and lymph node dissection, and after the surgery is completed, treatment such as adjuvant radiotherapy, chemotherapy or long-term clinical follow-up and observation is required.