Chalazion and granuloma have the potential to recur, but there is no clear data on which is more likely to recur. Chalazion is an obstruction of the glands forming a cyst on the eyelid, which may recur if not completely removed, and granuloma is a purulent inflammatory disease of the glands of the eyelid, which may recur if the inflammation is not well absorbed. Chalazion is a non-infectious disease, if the blepharoplasty gland obstruction caused by the patient’s eyelids appear obvious bumps, slowly can be absorbed, if can not be absorbed can be considered surgical excision. Chalazion is an infectious disease, acute suppurative infection of the blepharoplasty gland, mostly caused by Staphylococcus aureus infection, under the stimulation of inflammation, the patient may appear eyelid redness, swelling, heat and pain and other uncomfortable symptoms. Patients can follow the doctor’s instructions to use tobramycin ophthalmic ointment and other antibiotic treatment, if there is abscess formation, patients can be surgical incision drainage. It is recommended that patients with chalazion or granuloma consult a regular hospital in a timely manner to assess their condition and follow the doctor’s instructions for treatment.