There is no direct correlation between liver cysts and chronic viral hepatitis B. For hepatic cysts, in addition to their congenital causes, staying up late, exertion, and alcohol consumption can trigger the possibility of further aggravation or occurrence of hepatic cysts. For patients with chronic viral hepatitis B, there is no direct correlation between the occurrence of liver cysts and the further increase of liver cysts and patients with chronic viral hepatitis B. For patients with hepatitis B, blood should be drawn regularly to check the patient’s hepatitis B triple system, hepatitis B DNA and liver function to see if the patient has viral replication. If there is viral replication, antiviral therapy should be actively considered. For patients with liver cysts, the main thing is to review and confirm the diagnosis of liver cysts on a regular basis. If the diameter of liver cyst is less than five centimeters, it does not need to be treated and can be observed in time. If the diameter of liver cyst exceeds five centimeters, ultrasound-guided puncture and drainage of liver cysts or laparoscopic de-apicalization and drainage of liver cysts should be considered. After the above treatment, patients with liver cysts will mostly be cured.