Getting up with a bitter and dry mouth and bad breath may be caused by environmental factors, respiratory tract lesions, oral lesions, digestive tract lesions. 1. Environmental factors: if the sleeping environment is dry, do not get enough water, or the patient suffers from sleep apnea syndrome, thus appearing in the wake up after the mouth is bitter and dry and bad breath. 2. Respiratory lesions: because the mouth and respiratory tract are connected, if the patient suffers from chronic bronchitis, upper respiratory tract infections and other diseases, will often cough, cough phlegm, resulting in getting up after the mouth is bitter and dry and bad breath. 3. Oral lesions: life does not pay attention to oral hygiene, resulting in chronic inflammation of the oral cavity, so that the bacteria in the oral cavity for decomposition, fermentation of food residues in the oral cavity, thus causing a bitter and dry mouth after getting up and bad breath phenomenon. 4. Digestive tract lesions: If the patient suffers from chronic gastritis, dyspepsia, combined with bile reflux, Helicobacter pylori infection, which leads to a bitter and dry mouth and bad breath after getting up. It is recommended that patients go to a regular hospital in a timely manner, under the diagnosis of the doctor, according to the patient’s specific condition, to take targeted treatment, in order to avoid adverse effects on the body.