Hepatitis B patients with abnormal liver function will often show the following performance. If you are a hepatitis B patient and have some of the following symptoms, then you must stay alert and go to the hospital for liver function and ultrasound related examinations in a timely manner. Patients feel significantly weak in recent days, general malaise, loss of appetite, discomfort or pain in the liver area, abdominal distension, or both low fever. Physical examination reveals that some patients have a dull complexion, sclera and skin are often yellowish, and may have spider nevi and liver palms. Laboratory tests show that serum aminotransferases are elevated above 400 U/L. Generally, aminotransferases are elevated about 1 week earlier than bilirubin, and a few patients with severe disease may have enzyme-bile separation, significantly elevated bilirubin and bile acids, or a combination of decreased serum albumin, elevated globulin, prolonged prothrombin time, and varying degrees of elevated serum ALP and Y-GT. Immunological examination detected the relevant HBV antigen and antibody. Serum cholinesterase (ChE) is a reliable indicator of hepatocyte synthesis disorders, and ChE is significantly decreased in patients with severe active liver parenchymal lesions. Ultrasound examination: most patients have splenomegaly and increased width of the inner diameter of the portal vein, or both thickening of the gallbladder wall. A slight reduction in liver morphology is seen in chronic severe active hepatitis B. When the disease is stabilized, the liver size may return to normal in some patients. Hepatitis B slow-acting liver should be differentiated from the following diseases, such as acute viral hepatitis, hepatitis C slow-acting liver, hepatitis B combined with hepatitis D slow-acting liver, drug-induced acute liver injury, alcoholic hepatitis, active cirrhosis, primary biliary cirrhosis, hepatomegaly and α-antitrypsin deficiency.