The treatment of refractory nephrotic syndrome is mainly divided into searching for refractory causes, renal puncture biopsy, combined immunosuppressant treatment and other comprehensive treatments.
1. Searching for refractory causes: attention should be paid to whether there is a combination of infection, poor control of blood sugar, blood lipids and blood pressure, and a combination of thromboembolism and other conditions.
2. Renal puncture biopsy: For patients who cannot be relieved by active drug treatment, it is recommended to perform renal puncture biopsy again to clarify the pathological type and guide the treatment.
3. Combined immunosuppressant: under the guidance of pathological results, combined immunosuppressant such as cyclosporine, tacrolimus, cyclophosphamide, etc. should be used according to the condition, and urine routine and urine protein should be closely monitored to evaluate the condition.
4. Other comprehensive treatments: blood pressure and blood glucose changes should be closely monitored and maintained stable; attention should be paid to strengthening anticoagulation, lipid regulation and other comprehensive treatments.
Refractory nephrotic syndrome is recommended to consult regular hospitals in time and standardize the treatment under the guidance of physicians. Specific medication should be under the guidance of professional physicians to avoid unauthorized use of drugs.