Condyloma acuminatum can grow inside the anus. Condyloma acuminatum occurs mainly in the external genitalia and the moist areas of the mucous membrane of the skin around the anus. In men, it usually occurs in the glans, coronal groove, prepuce, urethra, penis and perineum, and in women, it usually occurs in the labia majora and minora, vaginal opening, clitoris, vagina, cervix, perineum and perianal area. In homosexuals, they occur in the anus and rectum, and in a few patients, they can occur in areas outside the anogenital area, such as the mouth, armpits, breasts, and toe crevices. The lesions are initially single, multiple, or clusters of small reddish granules with soft, slightly sharp tips, sometimes so small that they cannot be distinguished by eye. Later, the lesions may increase in size and may be papillary, cauliflower, or coronary in shape, white, pink, or black in color, and may be vesicular, oozing, ruptured, bleeding, or infected.