If the drug is taken three times a day, it is taken within an interval of eight hours, and the drug is taken once within eight hours, and three times a day for twenty-four hours is the best pharmacokinetics and pharmacokinetics, which will allow the fastest and maximum concentration of the drug to take effect. First, antimicrobials, antimicrobials are recommended to be taken three times a day, because the onset of action of antimicrobials is half an hour, the peak time is two hours, the half-life in the body is 8-12 hours, every eight hours to eat once, so that within twenty-four hours the body continues to have drug release concentration and release of drug active ingredients, so that the fastest degree of disease improvement. Second, the gastric mucosa protector and proton pump inhibitor, also need to be taken orally three times a day, usually before three meals, can play a role in protecting the gastric mucosa effect.