Among the bones of the human body, the skull is the hardest, it is the hard shell to protect the human brain. However, even if the skull is hard, it can not withstand the impact of some external gravity, it is inevitable that the skull defects such problems. Once the human skull is defective, the brain tissue lacks proper protection, the situation is quite dangerous. It must be clear that after the skull defect, the intracranial pressure is extremely unstable, which will directly affect the circulation of cerebrospinal fluid and blood in the skull, making it difficult for the brain tissue to operate normally, and also very unattractive from the appearance point of view. Therefore, it is necessary to have cranial repair surgery in time, both from the health point of view and aesthetic point of view. The choice of material is a crucial part of cranial repair surgery, and a good material can achieve a more ideal repair effect. Nowadays, titanium mesh material is widely used in some local hospitals, which is an improvement compared to the traditional bone cement and plexiglass, but it can’t avoid some defects. Commonly, patients will have postoperative infection and rejection phenomenon, and even cause scalp tissue breakage, and titanium mesh material is not very good thermal insulation, the patient will become very sensitive to hot and cold environments after the operation. Can titanium mesh for skull repair be used for MRI? This is also a very critical point, because titanium mesh is a metal material, it will interfere with the transmission of radiation, affecting the postoperative CT MRI and other examinations, interfering with the final diagnosis. Therefore, in order to better cranial bone repair surgery, we need a more advanced high-tech materials, polyether ether ketone-PEEK material is a good choice, the performance of this material is very excellent, comparable to the autologous cranial bone, do not have to worry about the infection problem after the operation, do not have to worry about the shadow interference to the relevant medical examination.