The key to glioma treatment is standardization. Glioma requires a combination of surgery, radiotherapy, and other treatments. Each part of the treatment is very important, and each part of the treatment is standardized, and each part of the treatment scores high, so that the maximum benefit can be obtained in the end, if one part of the treatment goes wrong or does not do the best, it is difficult to obtain the final success. The standardization includes but is not limited to: Diagnostic imaging: MRI is the main diagnostic imaging for glioma, and multiple imaging examinations are combined to make the diagnosis when necessary. The preoperative imaging diagnosis needs to predict whether the glioma is low-grade or high-grade, whether it is astral or oligodendroglial, the extent of tumor involvement, whether the timing of surgery is urgent, what kind of adjuvant is needed, the extent of resection, the short-term and long-term functional impairment, and the location of the specimen to be sent for pathology. Tumor resection range specification: The guidelines recommend maximum safe resection, which means that this resection degree is highly subjective, the highest goal is maximum safe resection, the same patient, choose different doctors and different hospitals, landing on a variety of possible situations. The guidelines recommend T2flair for low-grade gliomas to define the extent of resection, and enhanced T1-enhanced portions for high-grade gliomas as the extent of resection. The first step needs to be to try to remove the entire portion of the imaging abnormality that the guidelines define as requiring resection. In clinical practice, there are often many other factors that need to be considered to obtain a high score: e.g., tumor growth along the white matter fiber bundle (which needs to be considered when enlarging resection), non-functional areas that can be enlarged for excision (and need to be), the difference between the extent of enhancement and the site of abnormal angiogenesis in high-grade gliomas (non-enhancing but highly perfused areas also need to be excised), the difference between the extent of enhancement and the location of the choline peak in the wave spectrum (non-enhancing but high choline peak The Flair abnormalities in high-grade gliomas must contain tumors (which need to be resected). The recurrence of tumors soon after surgery is not excluded, but it is likely that what should be cut is not cut and what should be expanded is not expanded. Functional area localization specification: Functional area has rich connotation, not only language, movement and vision, but also executive, decision making, emotion and cognitive functions, etc. The connotation of localization needs to be combined with the social attributes of the patient and the patient’s demands, and the doctor should have a higher level of understanding. Functional area localization methods include awake craniotomy, functional MRI, anatomical location localization, functional neuronavigation, etc. Different medical institutions differ for historical reasons, and the reliability and complexity of each method varies, requiring rational use of their strengths to provide patients with individualized altered preservation options. For functional area glioma, there is no good means of functional localization, and surgery should be considered carefully. Standardization of resection extent judgment: The interpretation of resection extent is highly related to the defined tumor scope approach. For gliomas, even in the current era of molecular typing, the concept of maximum safe resection still applies, and maximum resection applies regardless of the type of glioma. The extent of resection also needs to be judged by objective criteria, consistent with those defining the extent of the tumor. There is also the need to standardize the timing of MRI scans, that is, MRI within 48 hours after surgery, preferably intraoperative MRI. Ask yourself whether the extent of resection has been objectively judged, and whether there is an MRI within 48h postoperatively? Or is there just an early postoperative cranial CT? Pathology diagnosis norms: the norms of pathology include the norms of histopathology and molecular pathology, and finally the norms of integrated pathology, which is closely related to the postoperative treatment and prognosis, without standardized diagnosis, there may be under-treatment or over-treatment. Postoperative radiotherapy standardization: Radiotherapy is the main adjuvant treatment for glioma. The outline and measurement of radiotherapy target areas given after surgery need to be standardized, and the timing of radiotherapy given after surgery also has standards. This phase is also an important stage of the treatment, as the areas that were not cut in place during surgery or not cut to the extreme should be taken into consideration during radiotherapy. Whether long course chemotherapy is needed needs to be considered in conjunction with the integrated diagnosis. Follow-up: Postoperative follow-up is an important tool to understand the effectiveness of glioma treatment dynamically and is an important guarantee of successful treatment. MRI is recommended every 6 months for low-grade glioma and every 3 months for high-grade glioma, and the frequency may be increased as needed. Often, patients who are able to follow up regularly in the early stages gradually relax their requirements with time and stop following up regularly or do not come for follow-up until they have symptoms again. Regular and standardized follow-up is an important basis for consolidating the effects of treatment. It is important to standardize each part of glioma treatment. Failure to achieve the best level in the previous part may bring stress or even disaster to the subsequent parts.