There is no such thing as the fastest way to get relief from sciatica, which can be caused by a herniated lumbar disc, pyriformis syndrome, or sciatic neuritis. There is no such thing as the fastest way to relieve sciatica. It can be treated with medication, physical therapy or surgery to address the cause of the condition. 1. Lumbar disc herniation: The herniated nucleus pulposus can cause sciatica because it presses on the sciatic nerve. Braking and bed rest are needed. Lumbar traction can be used to enlarge the intervertebral space and relieve nerve compression. Nutritional drugs such as methylcobalamin can be applied, and acupuncture and physiotherapy can also be used. Conservative treatment is ineffective to remove the herniated nucleus pulposus of the intervertebral disc with intervertebral foramenoscopy. 2. Piriformis syndrome: Piriformis syndrome is caused by the irritation and compression of the sciatic nerve due to the adhesion of the piriformis muscle, causing sciatic nerve pain. You can perform massage to relax the local muscles, or perform local closed injection, neuromuscular electrical stimulation therapy. 3. Sciatic neuritis: you can apply non-steroidal anti-inflammatory drugs, such as nimesulide dispersible tablets or diclofenac sodium enteric-coated tablets, oral nutritive nerve drugs, such as methylcobalamin, and ultrasound physiotherapy. Sciatica needs timely medical treatment, under the guidance of the doctor to take treatment for the cause.