The clinical manifestations of systemic scleroderma include skin damage and Raynaud’s phenomenon. Raynaud’s phenomenon is a manifestation in which only the fingers first appear to turn purple when exposed to cold, then turn white, and then slowly return to normal skin color. Myalgia, myalgia, and even myasthenia can also occur, as can symptoms in the joints, and other organs such as the heart and kidneys can also have corresponding clinical manifestations. Skin damage is mainly divided into three stages: 1. edema phase: diffuse swelling of the skin, skin lines will generally disappear, the surface is smooth; 2. sclerosis phase: the skin swelling disappears, the skin gradually hardens, adhering to the subcutaneous tissue, the surface will have a wax-like luster; 3. atrophy phase: skin atrophy becomes particularly thin, subcutaneous tissue and even muscle may be atrophied and hardened, showing a plank-like hardness, sometimes also Sometimes there is also hair loss, and the skin of the affected area generally rarely sweats.