Heartburn and oozing water from the mouth are considered to be caused by gastroesophageal reflux, cholecystitis, angina and other diseases. 1. Gastroesophageal reflux (GERD): This disease is a common clinical digestive system disease, mainly due to the presence of excessive obesity, gastric dilatation and other conditions, resulting in abnormal function of the esophageal anti-reflux structure, or due to long-term smoking, alcoholism and other behaviors, resulting in reduced resistance function of the esophageal mucosa. Patients often have symptoms such as reflux of gastric contents, heartburn and chest pain, which are manifested as heartburn and oozing from the mouth. 2. Cholecystitis: the cause of this disease is more complex, usually due to the presence of gallbladder stones, causing biliary obstruction, or due to bacterial, viral and other pathogenic infections. The disease often leads to patients with epigastric radiating pain, some patients can appear chest pain, at the same time, patients will also appear nausea, vomiting, belching (hiccups), acid reflux and other symptoms, and some patients will appear heart pain in the mouth seepage of water. 3. angina: the disease is mainly due to patients with coronary artery atherosclerotic plaque, resulting in myocardial ischemia. Patients often appear more obvious heart boring, pain, pressure and other symptoms, some patients will also be accompanied by nausea, and nausea will lead to increased secretion of saliva in the patient’s mouth, thus appearing in the case of heart pain and water seepage from the mouth. It is recommended that patients with recent symptoms of heartburn and watery mouth should seek medical attention as soon as possible to determine the cause of the problem.