What should people with chronic viral hepatitis B with major third-positive disease pay attention to in their daily lives? We all know that chronic viral hepatitis B can be transmitted through blood, mother-to-child and sexual contact. However, if a patient with chronic viral hepatitis B has a very low level of hepatitis B virus and normal liver function, then hepatitis B patients tend to be very less infectious. So the first and most important thing for patients with chronic viral hepatitis B is to adhere to antiviral therapy. Long-term and effective antiviral treatment can be very good control of hepatitis B virus content, to avoid hepatitis B virus proliferation, reduce liver damage aggravation. The most commonly used antiviral drugs are entecavir, adefovir, lamivudine and so on. Secondly, patients with chronic viral hepatitis B need to regularly review their liver function and find elevated liver cell transaminases and bilirubin and other indicators need timely liver support therapy. Commonly used hepatoprotective drugs include glutathione, polyenyl phosphatidylcholine, regan, isoglycyrrhetinic acid and so on. Finally, patients with chronic viral hepatitis B need to strengthen nutritional support therapy, eat more high-protein, low-fat, high-fiber foods, such as eggs, tofu, soybean skin, soy milk, milk, fresh vegetables and fruits. Exercise appropriately to strengthen the body’s resistance, try to go to bed early and wake up early, do not stay up late, and quit smoking and drinking. Reduce the burden on the liver as much as possible and promote the recovery of damaged liver cells.