Prostate cancer has become the number one killer of men over the age of 60. At present, there are many treatment methods for prostate cancer, including surgery, endocrine therapy, chemotherapy and radiation therapy, etc. Which therapy is suitable for patients depends on individual differences, especially those who cannot be treated surgically and those who cannot be treated with endocrine therapy and chemotherapy are very tricky to treat. Our department has recently introduced the most advanced treatment technology in the world – argon helium cryotherapy. This technique does not require an incision. After saddle anesthesia or basic anesthesia plus local anesthesia, a special probe is inserted into the pre-selected area of the prostate tumor via the perineum under transrectal ultrasound guidance and monitoring. High-pressure argon gas is injected by special equipment to bring the treatment area to an ultra-low temperature of more than minus 100 degrees Celsius within a few minutes, and after 5 to 15 minutes the high-pressure helium gas warms up as a treatment cycle. After the freezing and melting process, the tumor tissues in the treatment area will be ablated, so that two cycles will complete one treatment process. Less bleeding and faster recovery. Although this treatment is simple, a catheter must be left in place before the procedure, and hot saline must be continuously instilled to protect the urethra during and 1 to 2 hours after the procedure.