When it comes to chronic renal failure, many people may not think of it, while when it comes to uremia, they talk about the sense of color. In fact, uremia is the end stage of chronic renal failure. It can be seen that chronic renal failure is the main culprit of human health. Chronic renal failure is a variety of chronic kidney disease development to the late stage of a clinical syndrome. Such as chronic glomerulonephritis, such as primary glomerular disease, diabetes mellitus, hypertension, erythema pigmentosum, anaphylactic purpura, hepatitis B kidney, multiple myeloma, urinary tract infection, polycystic kidneys, urinary stones, prostate enlargement, medication renal damage, etc., can be developed into chronic renal failure. Once the disease is formed, its trend is bound to move step by step towards the terminal stage. Therefore, early diagnosis and early treatment to slow down the forward march of chronic renal failure is particularly important. To achieve this goal, the best choice is still the combination of Chinese and Western medicine. Of course, the earlier the treatment, the better the result. Early detection of chronic renal failure is an important part of implementing early treatment to stop its development. However, due to the extremely strong compensatory function of human kidney, even if the patient has lost more than 50% of renal function, he/she may not have any symptoms. We often come across patients who are suddenly found to be suffering from chronic renal failure when they are diagnosed and treated for other diseases or during routine medical checkups. Many of these cases are already in a serious stage. In fact, these patients are easy to ignore because of the hidden condition or atypical symptoms, but not without signs. Here are a few noteworthy signals. 1, drowsiness and fatigue, yellowish color, reduced diet, nausea and vomiting in the morning light, no obvious skin rash and scratching, sudden swelling, decreased urine output, increased nocturia. 2, suffering from diabetes mellitus, hypertension, gout, anaphylactic purpura, hepatitis B, urinary stones, etc., in particular, we should always check the renal function, be alert to the occurrence of chronic renal failure. 3, the long-term use of painkillers, often take traditional Chinese medicine, and the use of Chinese herbal medicine. If you are a patient with chronic renal failure, you should always take Chinese medicines containing aristolochic acid such as mouton, antipyrine and aristolochic acid, and often inject nephrotoxic antimicrobial drugs. Anyone with the above signals should go to the hospital for frequent checkups in order to detect the disease at an early stage. The combination of Chinese and Western medicine treatment programs can play a synergistic role in improving the therapeutic effect. Chinese medicine often adopts treatments such as benefiting the kidney and strengthening the spleen, activating blood circulation and removing blood stasis, and draining turbidity and detoxifying the toxin, with a variety of means, such as soups, injections, retention enemas, medicinal baths, foot baths, and so on. Western medicine is based on low-protein diet plus essential amino acid therapy, which can effectively correct reversible factors, such as infection, heart failure, hypertension, control of blood glucose, lipid regulation and so on. In specific implementation, different comprehensive treatment measures should be developed for different patients. Patients should follow the doctor’s instructions, relax and accept the treatment with confidence in order to achieve good therapeutic effects and achieve the goal of delaying the deterioration of chronic renal failure.