There have been numerous tragedies caused by postpartum depression, and according to the American Psychological Association, up to one in seven women experience postpartum depression after childbirth, which can be severe enough to seriously harm themselves and their babies’ safety. Can postpartum depression heal itself? Postpartum depression usually occurs within 4 weeks after delivery. Due to the influence of changes in hormone levels, there is a physiological nervousness after delivery, especially for first-time mothers, who are afraid of not taking good care of their babies and various problems, and feel self-blame, while many patients are not aware of it, and family members need to pay more attention to such a serious illness, which should not be taken lightly. The difference between postpartum depression and postpartum depression is that postpartum depression has reached the diagnostic criteria of the disease, while postpartum depression is just a mood, postpartum depression may develop into postpartum depression if it is not effectively corrected. Postpartum depression is a self-limiting disease and can heal itself, but there are certain conditions for self-healing. Patients with milder disease and shorter duration of disease generally heal better, and most patients can heal themselves within six months. Patients with severe depression symptoms, severe cases even have the possibility of suicide or harming the baby, and long periods of time without relief, self-healing is less likely, such patients need to be treated with medication or other forms of intervention. The incidence of postpartum depression is high and prevention is the key. Postpartum mothers should pay attention to learning about postpartum depression, early diagnosis and early treatment, and for mothers with a history of postpartum depression and those with a family history, they need to pay more attention to the risk of postpartum depression.