Potassium permanganate has a local anti-inflammatory and anti-swelling effect, and has a certain therapeutic effect on anal fissures. Combined with warm water sitz baths, it can reduce pain and control inflammation, but cannot completely cure anal fissures. The main clinical manifestations of anal fissures are pain around the anus during and after defecation, constipation, connective tissue external hemorrhoids, anal papillary hypertrophy, and bleeding. The most common cause is caused by constipation. In the early stage, you can drink more water, exercise more, eat more vegetables and fruits, keep your bowels open, and take a sitz bath with 1/5000 potassium permanganate solution twice a day for about 20 minutes each time, and wipe dry after the sitz bath. Use Ma Yinglong hemorrhoid cream topically in the morning and Jiuhua hemorrhoid suppository topically before going to bed for treatment. Chronic anal fissures have mostly formed ulcers and are difficult to be cured by simple medication, so you can consider anal dilation treatment, but it is easy to recur. Or surgical treatment, cut the internal anal sphincter that can be completely cured, pain, bleeding disappeared.