Clinically, we must master strict diagnostic criteria, and never easily make the diagnosis of coronary heart disease, so as not to bring mental burden and physical damage to the patient, and cause a great waste of drugs, which will have a negative impact on the family and society. However, if the diagnostic conditions are too strict, the real patients with coronary heart disease may be missed and the diagnosis and treatment of patients may be delayed. The diagnostic conditions mainly include: (1) a typical angina attack or myocardial infarction without evidence of severe aortic stenosis, incomplete closure, or cardiomyopathy. (2 ） Significant myocardial ischemic manifestations on ECG at rest, ischemic changes on dynamic ECG, positive ECG exercise test, or positive changes suggested by cardiac ultrasound, nuclear examination, cardiac CT or MRI, or cardiography, any of these typical positive changes can be used as an objective basis for myocardial ischemia. And no other causes (such as various heart diseases, significant anemia, obstructive pulmonary emphysema, vegetative nervous disorders, application of digitalis drugs and electrolyte disorders, etc.) can be explained. If the patient only has ischemic manifestations on objective examination such as electrocardiogram without angina pectoris, it can be diagnosed as asymptomatic myocardial ischemia. (3 ) Patients over 40 years of age with enlarged heart, heart failure, and papillary muscle dysfunction that cannot be explained by myocardial disease or other causes and two of the following three: (1) hypertensive disease; (2) hypercholesterolemia; and (3) diabetes mellitus. Therefore, to diagnose coronary artery disease, it is necessary to comprehensively consider the patient’s genetics, risk factors, poor lifestyle, age, gender, medical history, symptoms, signs and physical and chemical examination results, and also to exclude other related diseases to be as comprehensive, objective and accurate as possible.