Endogenous creatinine clearance is not strictly a glomerular filtration rate, but glomerular filtration rate is generally used clinically as a substitute for endogenous creatinine clearance to assess renal function.
Glomerular filtration rate (GFR) refers to the number of milliliters of plasma fluid filtered through the glomerulus per unit of time, and the normal range is 120-160 ml/min.
Endogenous creatinine clearance refers to the total removal of creatinine from a number of milliliters of blood by the kidneys per unit of time, and the normal range is 80 to 120 ml/min. In the elderly, there is a tendency for endogenous creatinine clearance values to decline naturally with age.
To determine GFR, renal plasma clearance tests for many substances have been devised clinically, with endogenous creatinine clearance being the more commonly used. All creatinine in the blood is generally filtered through the glomerulus, not absorbed by the renal tubules and rarely excreted by the tubules. Therefore, endogenous creatinine clearance is generally greater than the actual GFR, but it can basically represent the GFR.
If patients have any discomfort, it is recommended to consult regular hospitals in time, complete relevant examinations as prescribed by doctors, and carry out targeted treatment.