Patients with tuberculosis may cough up sputum, which may be white or yellow in color. Yellow sputum may be due to bacterial infection. If the patient develops cough and sputum, it is recommended to complete blood tests, C-reactive protein, sputum culture and other related tests to evaluate whether there is a combination of bacterial infection and other related pathogens. If the patient’s white blood cells are elevated and C-reactive protein is increased, it is considered that the patient has a combined bacterial infection, which needs to be treated with antibiotics along with anti-tuberculosis treatment. For mild cases, oral antibiotics can be given, such as cefixime, moxifloxacin, azithromycin, etc. If the patient’s bacterial infection is more serious, intravenous antibiotics can be given, and the commonly used antibiotics include cefoperazone sodium sulphadiazine sodium, moxifloxacin, cefazolin pentahydrate sodium and so on.