Marshall-White syndrome is not related to smoking and is a congenital vascular development problem caused by autonomic disorders and vasodilatory dysfunction. Marshall-White syndrome patients often have pale white spots on the ends of their limbs. When the limbs are prolongedly draped, some of the vasoconstrictive dysregulation is impaired, and the microcirculation is impaired at the ends of the limbs, and the white spots become more obvious. When the arm is lifted, normal blood flows into the heart, and the color of the white spots becomes lighter than normal skin. The white spots reappear when the arm is lowered. Marshall-White syndrome generally does not affect the life, and does not require special treatment, it is recommended that patients go to regular hospitals, complete the relevant examinations, under the guidance of doctors to standardize the treatment.