Whether or not you can take medication after the hepatitis B vaccination is related to the specific type of medication, usually glucocorticoids, immunosuppressants, etc. cannot be taken. In addition, antibiotic drugs and anti-allergy drugs should not be used within three days to avoid affecting the vaccination effect. And some other drugs for treating chronic diseases such as diabetes, hyperlipidemia and hypertension do not affect the use of drugs after hepatitis B vaccination. Glucocorticoids and immunosuppressants, the former are mostly used for the treatment of primary or secondary (pituitary) hyperalgesia and various allergic reactive diseases, such as angioedema, acute urticaria, contact dermatitis, serum sickness, anaphylaxis, etc., and the latter are mostly used for rheumatoid arthritis, lupus erythematosus, dry syndrome and other diseases. The above drugs may suppress the immune response of the body and reduce the preventive effect of hepatitis B vaccine, or cause adverse reactions such as fever. There are also some precautions to take after receiving the hepatitis B vaccine. Temporary symptoms such as redness, swelling and pain may occur at the injection site after vaccination, which usually disappear on their own after 1-3 days. It is not recommended to take a bath within 24 hours after the hepatitis B vaccination, and it is important to take more rest and not to stay up too late. Try to eat a light diet, do not eat spicy and greasy food, avoid drinking alcohol, do not drink strong tea and coffee, and do not do too intense exercise to avoid unnecessary injuries.