Why patients with kidney disease are afraid of cold, because patients with kidney disease have poor body resistance, and if the cold occurs again, it may make the kidney disease become more serious. Most of the kidney diseases are related to the deposition of immune complexes, some bacteria, viruses, and their metabolites will appear in the body when the patient has a cold, and the antibody reaction in the body will form circulating immune complexes, when the immune complexes are deposited and attached to the glomerulus for a long time, it will make the kidney tissues hurt and cause kidney diseases, so patients with kidney disease will make the disease more serious. So patients must go to the hospital for timely treatment after a cold, not to take cold medicine or antibiotics on their own, otherwise it will cause an allergic reaction in the body, resulting in adverse reactions in the blood system, kidneys or nervous system, leading to nephritis.