The first step to take when suffering from dyslipidemia is dietary therapy and lifestyle modification. Although this is very important, not every patient can adhere to it for a long time, and its lipid-regulating effect only works for about 10% of patients. Therefore, for patients whose lifestyles do not work, taking lipid-regulating drugs becomes the way to go. In the face of the increasing number of lipid-regulating drugs available, how to choose according to the characteristics of the disease? What should I pay attention to? These are the most important questions for patients with dyslipidemia, and we would like to give you some suggestions based on our clinical experience. Sulforaphane (generic name: simvastatin) belongs to the statin class of lipid regulating drugs, which are the most widely used first-line lipid regulating drugs in the world and are the first choice for the treatment of hypercholesterolemia. Features: It mainly reduces serum total cholesterol (TC) and “bad” cholesterol (LDL-C), and also lowers triglycerides, with significant efficacy, but is less effective in raising “good” cholesterol (HDL-C). C) is slightly less effective. It is contraindicated in cases of biliary depression, active liver disease, pregnant and lactating women, and in cases of allergy. Monitor liver and kidney function and creatine kinase (CK) during use, and seek medical attention if muscle pain or weakness occurs. Statin lipid regulators are also available: Lipitor (atorvastatin), Meperidine (pravastatin), Lysergol capsules (fluvastatin), etc. Lipinex (generic name: fenofibrate) belongs to the beta class of lipid regulators. It is the first choice for hypertriglyceridemia because it mainly lowers triglycerides and cholesterol. Use note a few patients have gastrointestinal reactions, skin pruritus, and transient liver and kidney function changes, need to regularly check liver and kidney function. Long-term application may increase the incidence of cholelithiasis and is contraindicated in pregnant and lactating women. Betablocker lipid regulators are also available: Bifidol (benzofibrate), Norhom (gemfibezil), etc. Ipin (generic name: Acipimox) is a lipid regulator of the niacin class. This class of drugs has significant lipid regulating effect only at high doses, and its application is limited by relatively more adverse effects. FeaturesNicotinic acid lipid regulators can be used in combination with statins in the treatment of mixed dyslipidemia (especially elevated serum total cholesterol (TC), low-density lipoprotein cholesterol (LDL-C), and serum triglycerides (TG)) to reduce both the dose of statins and the occurrence of adverse reactions. Note that common adverse reactions to niacin include flushing, itching of the skin, and gastrointestinal discomfort, so it is not easily tolerated. In addition, it can also cause and aggravate gastric and duodenal ulcers and lead to increased blood uric acid, etc. Long-term application requires monitoring of liver and kidney function. Patients with peptic ulcer, gout, hyperuricemia, diabetes mellitus and active liver disease should avoid taking high doses of niacin as much as possible. Cholestyramine (generic name: koleleneamine) is a bile acid chelator. This drug is currently the drug of choice for the treatment of dyslipidemia in children and adolescents. It mainly reduces total cholesterol (TC) and has significant effects with few adverse effects. Caution for use This product may cause malabsorption of fat, fat-soluble vitamins and folic acid in long-term use, which may affect the growth and development of children and adolescents. Therefore, in addition to close monitoring of height and weight, fat-soluble vitamins such as vitamin A, vitamin D, vitamin K and calcium salts should be supplemented appropriately. Cholinesterone (Colestipol) also belongs to this category of drugs. Chinese patent medicines and other commonly used medicines include Lipitor capsules, Blood Lipid Capsules and Tylenol Capsules. Strictly speaking, these drugs are not purely proprietary Chinese medicines, but are a combination of Chinese and Western medicines. The main ingredients of Lipitor and Lipokang are red currant and contain a considerable dose of lovastatin, which should be used with statin or beta lipid regulators with caution to avoid overdose. Sea fish oil preparations, such as polyenkang pills, can also be used to regulate blood lipids. The effectiveness of these lipid regulators is relatively weak, and they are generally only suitable for mild to moderate dyslipidemia, with relatively few adverse effects.