The principle of treating condyloma acuminata is to make a clear diagnosis, exclude mixed infections and tumor changes, by choosing a variety of different methods to remove exophytic warts, remove subclinical infections, improve the immunity of the patient’s body, and reduce the recurrence rate. 1, chemotherapy: commonly used drugs including tincture of haematoxylin, fluorouracil gel, polymethylsulfonyl, trichloroacetic acid, paterin, etc. 2, physical therapy: including liquid nitrogen freezing, CO2 laser, delta-aminoketovaleric acid photodynamic therapy (ALA-PDT), microwave, etc. 3.Surgical therapy: including electrosurgical treatment, surgical excision, etc. 4.Immunotherapy: including topical imiquimod cream, interferon; systemic use of interferon, cytokine, levamisole, transfer factor, thymidine, immune ribonucleic acid, isotretinoin, etc. 5.Prevention: cervical cancer vaccine. Human papillomavirus (HPV) types 16 and 18 are the main causes of cervical cancer, and more than 70% of cervical cancers are related to these two types. Therefore, the U.S. FDA has recommended HPV vaccine since 2006 for routine vaccination of all women between 11 and 26 years of age to effectively prevent infection with HPV types 6, 11, 16, and 18. cardasil is a quadrivalent vaccine for HPV types 6, 11, 16, and 18, given once at months 0, 2, and 6. cervarix is a bivalent vaccine for HPV types 16 and 18 Cervarix is a bivalent HPV 16 and 18 vaccine, given once in months 0, 1 and 6. The physician chooses the method according to the patient’s specific situation, based on the basic principles of effectiveness, simplicity, safety, and no scarring. Other sexually transmitted diseases that may accompany the vaccination should also be treated promptly and effectively, and protective measures should be taken to avoid transmission to others. The patient’s spouse or sexual partner should be examined and treated at the same time if he or she has condyloma acuminata. Otherwise, the patient can be reinfected.