There are several treatment options for patients with obstructive azoospermia: IVF with epididymal puncture or vasectomy with microscopic vasectomy? In my opinion, the choice should be made according to the actual situation of the patient. The following are the advantages and disadvantages of the two methods: 1. economy: in terms of cost, microscopic surgery is less expensive, usually costing about 15,000, while IVF costs 30-40,000; 2. success rate: the success rate of recanalization is 70% and the pregnancy rate of the spouse is 40%, while the success rate of IVF is about 30%. 3.Effects: The way of pregnancy after recanalization is more natural and can meet the requirements of having children again; IVF injects selected sperm into the follicles through artificial means and can eliminate certain vulnerable embryos through genetic screening.