Frequent mycoplasma infections in children may be caused by incomplete cure of the disease, low resistance or cross infection. The specific cause of the disease should be clarified, and then targeted treatment. The child should be given more nutrition, and timely increase and decrease clothing, strengthen care. 1, not completely cured: because the respiratory mucosa is relatively thin, blood is rich, once infected with mycoplasma, the bacteria can be long-term existence. If not treated in time or not completely cured, the child is prone to frequent mycoplasma infections; 2, low resistance: due to cold, unreasonable diet, drinking less water, etc., resulting in the child’s resistance to decline, and then prone to repeated infections, that is, frequent mycoplasma infections. Parents should carefully observe the changes in the child, and pay attention to strengthening nutrition, moderate exercise to improve immunity, so that it remains in a healthy, stable state; 3, cross-infection: If the child is in a relatively closed and crowded environment, it is easy to cross-infection resulting in frequent mycoplasma infections in children. Because the pathogen can be spread through droplets, it is recommended to take the child to avoid crowded places, avoid excessive contact with the crowd, and wear a mask to prevent when going out. Children with symptoms of mycoplasma infection should be actively treated under the guidance of a medical professional. Generally, mycoplasma infection is relatively sensitive to macrolides, such as erythromycin and azithromycin, and patients need to take the medication on time and in the right amount in order to cure the disease. In addition, in daily life, parents should urge their children to take physical exercise in appropriate amounts, while eating a balanced diet and drinking more water. Pay attention to increase and decrease clothes when the climate changes.