Ankle arthritis refers to the inflammation of the ankle joint. There is no definite “best and most effective” treatment method, and it can be treated by general treatment, medication, physical therapy and surgery. The more common ones are osteoarthritis, rheumatoid arthritis, gouty arthritis and infectious arthritis of ankle joint. 1. Osteoarthritis: it is a degenerative change in the ankle joint, which is related to long-term chronic strain and trauma, etc. The severe pain can be treated with painkillers such as ibuprofen, and physical therapy such as localized hot compresses and baking, as well as injection of sodium hyaluronate into the joint cavity if necessary. If conservative treatment is ineffective and the symptoms are severe, surgical treatment such as ankle fusion is feasible. 2. Rheumatoid arthritis: related to heredity and autoimmunity, non-steroidal drugs such as diclofenac sodium can be given for treatment, and glucocorticoid drugs such as prednisone and anti-rheumatic drugs such as methotrexate can be given for treatment. 3. Gouty arthritis: it is related to the excessive content of uric acid in the body, colchicine can be given to treat in the acute stage, and allopurinol can be given to reduce uric acid during the remission period. 4. Infectious arthritis: mostly due to bacterial infection, can be given amoxicillin, levofloxacin and other antibacterial drugs anti-infection treatment, the formation of abscesses need to be surgically incised and drained. Suffering from ankle arthritis is recommended to go to the hospital, improve the auxiliary examination, in order to clarify the cause and severity of the disease, follow the doctor’s instructions for targeted treatment, the drug needs to be used in accordance with the doctor’s instructions, so as not to cause adverse consequences.