The indications of cimetidine are mainly: 1, treatment of active duodenal ulcer and prevention of recurrence of duodenal ulcer; 2, treatment of gastric ulcer; 3, treatment of reflux esophagitis; 4, treatment of gastrinoma; 5, prevention and treatment of stress and drug ulcer; 6, treatment of peptic ulcer complicated by bleeding; 7, can be used in the treatment of immune deficiency caused by various reasons and adjuvant treatment of tumors; 8, for the treatment of herpes zoster, other herpetic infections including genitalia, 9, female androgenic alopecia, acne, hirsutism in women, herpes zoster, etc.