Pneumoconiosis is a disease in which fibrosis of the lung tissue occurs mainly due to inhalation of dust during production activities. The main occupations that cause pneumoconiosis are: mining of metal mines, wind drilling, blasting and coal mining in coal mines; metal smelting; foundry sand preparation, sand blasting, welding operations; stone mining, crushing; tunneling, blasting, etc. The most common types of pneumoconiosis are coal workers’ pneumoconiosis, silicosis, and welders’ pneumoconiosis, with silicosis and coal workers’ pneumoconiosis accounting for a total of 90 percent. What is even more frightening is that most people suffer from pneumoconiosis without even knowing it! The onset of pneumoconiosis is slow, with no obvious symptoms in the early stages, or only very mild symptoms, and is often detected during a physical examination. However, as the disease progresses, symptoms, mainly coughing, chest tightness and shortness of breath, appear. The most common symptom is shortness of breath. The lighter ones feel shortness of breath when doing heavy work, which improves after rest; the more severe ones feel shortness of breath when doing some light work or walking upstairs; the severe ones also have chest tightness and shortness of breath when resting; and are often accompanied by coughing, coughing up sputum, weakness, wasting, hemoptysis, etc. Common complications of pneumoconiosis include tuberculosis, chronic bronchitis, and spontaneous pneumothorax. As the condition worsens and complications arise, the patient eventually becomes totally incapacitated, unable to take care of himself, and eventually becomes life-threatening due to respiratory failure. Currently, the best treatment for pneumoconiosis is large volume whole lung lavage (WLL), which involves filling the lungs with sterile physiological saline and washing out the dust and other harmful substances from the alveoli through water flushing, which is equivalent to giving the lungs a bath, and is a treatment to eliminate the cause of the disease, which can slow down the progress of pneumoconiosis and cannot be replaced by drugs. In addition, WLL can improve the symptoms and lung function of pneumoconiosis, improve the quality of life and maintain their working ability. Since this technology was introduced in our hospital in 2006, more than 2000 cases of lung lavage have been performed, with positive and safe clinical results. However, the effect of WLL treatment is mainly related to the course of pneumoconiosis. In the early stage of pneumoconiosis (stage 0 to I), a large amount of dust is still in the alveoli, and WLL can wash out the dust in the alveoli, so the treatment is effective and less expensive; in the late stage of pneumoconiosis (stage III), a large amount of dust has been transferred to the interstitial space, and WLL cannot wash out the dust in the interstitial space, so the treatment is much less effective than in the early stage and more expensive. In addition, advanced stage of pneumoconiosis often cannot be treated with WLL because of complications. In principle, pneumoconiosis patients should not be exposed to dust after large volume whole lung lavage, and if they are exposed to dust again, they should undergo WLL again after 3 to 5 years to remove residual dust from the lung and consolidate the therapeutic effect.