Infants are children less than one week old, at this time the liver and kidney function is not fully developed, so once infants have a cold and nasal congestion, do not immediately take common adult drugs. Since cold is a self-limiting disease, as long as the symptoms are not serious, the symptoms can be relieved within a week by proper rest, adequate water and light diet. If you have a fever and want to take medication to reduce discomfort in infants, you can take oral antipyretics, such as acetaminophen or ibuprofen. If the nasal congestion is caused by a cold, it is recommended to wash the baby’s nose with saline, spraying saline through one nostril and then flushing the snot out of the other nostril, or putting a wet hot towel on the root of the baby’s nose. In addition, patting the back and holding the baby vertically can also relieve the baby’s discomfort. If infants have acute nasal congestion, ephedrine nasal drops can be considered, but long-term use of ephedrine nasal drops is not recommended to avoid the adverse effects it brings, such as palpitations, tremors, and insomnia. When an infant has a cold and nasal congestion, due to the protective effect of the nasal mucosa, the infant will feel discomfort and behave differently from usual behavior, crying and fussing, hyperactivity and gasping for air. Parents need to pay more attention to early detection and early treatment.