When it comes to “jaundice”, people easily think of hepatitis and liver cancer, and even treat the disease as a liver disease and miss it. In fact, jaundice and liver disease are not twins, and jaundice is not always associated with liver disease. Jaundice can be caused by many factors, and pancreatic cancer is one of the major killers. Pancreatic cancer is a highly malignant tumor that seriously threatens people’s survival and health, and there is a significant rising trend in recent years. Its high incidence age is 40-70 years old, and more men than women. The occurrence of pancreatic cancer is closely related to smoking, diabetes, gallstone disease, alcohol consumption (including beer), chronic pancreatitis, and eating a high-fat and high-protein diet. Pancreatic cancer lacks specificity in terms of symptoms. As the tumor continues to grow, patients will only gradually develop some symptoms, such as upper abdominal discomfort, jaundice, vague pain, loss of appetite, nausea and vomiting, weight loss, and pain in the lower back. However, since these symptoms are not unique to pancreatic cancer, they are often overlooked by patients and even doctors, and by the time pancreatic cancer is diagnosed, the disease has already developed to the middle and late stages and lost the chance of treatment. Therefore, early diagnosis and early treatment are the keys to improve the prognosis of pancreatic cancer.