The principle of Botox treatment for hyperhidrosis is that sweat mainly comes from sweat glands, and acetylcholine can make sweat glands secrete, if the body’s acetylcholine secretion is blocked, sweat gland secretion will stop. Botox injections can play a role in paralyzing the nerves, thus blocking or reducing the secretion of acetylcholine and finally stopping the patient’s symptoms of profuse sweating. This treatment is safe and reliable, the treatment is less painful, and complications rarely occur. However, if improperly operated, the following risks may also exist: 1. pain, edema and bleeding at the injection site, but no treatment is needed, and it will subside in a few days; 2. after repeated injections, the body produces antibodies to botulinum toxin, and the efficacy of re-injection is not obvious, so other brands or doses of botulinum toxin can be used for treatment, or other treatment methods can be chosen; 3. muscle atrophy at the injection site, and slight depressions and other phenomena should be promptly sought medical treatment; 4, local infection, the armpit itself is a good medium due to the excessive secretion of special fatty acids, once the resistance is easy to infect, or even normal flora infection. Generally in botulinum toxin injection 48-72 hours sweating significantly reduced, 1 week after the sweating basically disappeared, the effect can be maintained for 6-8 months, there are some patients can be up to 19 months. The maintenance time is related to the patient’s own condition, medication and the patient’s postoperative care routine.