HPV52 and 68 positivity is the infection of two subtypes of human papillomavirus, high-risk type, which is a multi-type HPV infection. If HPV52 and 68 infection persists, it can cause cervical precancerous lesions or even cervical cancer. If there is no abnormality in the TCT examination, we can refer to colposcopy, and carry out multi-point biopsy of the cervix under colposcopy. If there is no abnormality in the histologic examination, we can give anti-viral drugs to carry out effective treatment, for example, we can give thymopeptide tablets orally, to enhance the body’s resistance, which is beneficial to the conversion of HPV52 and 68 positivity. Can also be given to the line of anti-HPV infection of vaginal preparations for the drug, such as can be given to the alpha-interferon pessary or given to the Rebeson, anti-HPV bioprotein dressing and other drugs for vaginal drug, at the end of the treatment, should be regularly re-examined until the HPV52 and 68 positivity to the negative.