Gynecological mycoplasma infections are treated with sensitive antibiotics and are usually cured in about 1-2 weeks. Mycoplasma is a common pathogenic microorganism of female genital tract and urinary tract infections, causing mycoplasma urethritis and mycoplasma vaginitis. It is necessary to select sensitive antibiotics for treatment according to clinical manifestations, combined with urine examination, vaginal discharge examination, and culture and drug sensitivity test of pathogenic microorganisms, commonly used macrolide antibiotics, commonly used drugs are roxithromycin, azithromycin, clarithromycin, etc. Generally about 1-2 weeks can be cured, but mycoplasma infection is prone to recurrence, should also be regularly reviewed in the hospital after cure. Mycoplasma infection can be transmitted to the spouse through sexual life, so during the infection period should avoid unprotected sex, towels, basins and other personal items should be used separately, and fully disinfected to avoid the transmission to family members.