At present, with the continuous improvement of people’s quality of life and the further deepening of the understanding of constipation, the hazards of constipation are gradually recognized and strengthened. Constipation not only makes it difficult to defecate but also brings many hazards to physical and mental health. Constipation can also be caused by prolonged retention of feces in the intestinal tract, abnormal fermentation, corruption, which produces a large number of toxins harmful to human body, anxiety, depression, abdominal distension, tasteless diet, easily lead to skin itching, facial pigmentation, and rashes. The harm of constipation is not only limited to gastrointestinal tract dysfunction, but also induces cardiovascular and cerebrovascular diseases. Patients suffering from coronary heart disease, constipation when forceful defecation, can cause myocardial ischemia, palpitations, shortness of breath in mild cases, or sudden death in severe cases. Patients with hypertension constipation, forceful defecation can increase blood pressure, resulting in cerebral ischemia, hypoxia, dizziness, brain swelling, heavy head and light feet. Constipation with cirrhosis of the liver can lead to rupture of the esophagogastric fundic vein and gastrointestinal hemorrhage.