What women over 35 years of age need to pay attention to when having a second child 1. The chances of conception are significantly lower for women over 35 years of age, and only 1/100th of women over 40 years of age have a chance of conceiving each menstrual cycle. If you are actively trying for 6 months and still not pregnant, a more active approach is to consult a reproductive medicine specialist and receive the necessary medical assistance. 2. For women over the age of 40, there is a relatively high risk of miscarriage, an increased risk of pregnancy complications such as surgical delivery, diabetes, intrauterine growth restriction and low birth weight babies, and the need for screening for certain diseases such as diabetes and hypertension prior to conception. 3. It is generally recommended that both partners undergo a comprehensive medical examination that includes a preconception checkup. Obstetrics and gynecology should include: gynecological examination, cervical cytology screening (currently mainly TCT), ultrasound of the uterus and both adnexa. If financial conditions allow, screening for both high-risk HPV virus and TORCH testing is recommended. 4. Take one 0.4mg tablet of folic acid daily starting three months before the planned pregnancy until three months after successful conception. If the pregnancy is unplanned and there is no folic acid supplementation in advance, as long as women are not extremely paranoid or severely malnourished, they should not overly panic and just start taking it in time. 5. For women with regular menstruation, maintaining a regular sex life (2-3 times/week) from the last clean period can help increase the chance of conception. The 6 days before ovulation is medically defined as the “conception window”, if you can maintain a frequent sex life within these 6 days / 1-2 days will get the maximum chance of conception. If you have a less frequent sex life, or if you live in two places, or if one of you travels a lot, it is recommended to master some methods to predict ovulation, such as measuring basal body temperature and using ovulation test strips, which will help to improve the conception rate.