Prostate cause perineal pain may be prostatitis, urethritis, prostate abscess and other causes, need to eat amoxicillin, ceftriaxone, tamsulosin hydrochloride, metronidazole and other drugs for the cause. 1. prostatitis: for bacterial prostatitis, patients need to follow the doctor’s instructions to take penicillin antibiotics, such as amoxicillin, penicillin G, etc., or cefazolin, cefuroxime and other cephalosporin drugs. At the same time, it is also necessary to follow the doctor’s instructions to take doxazosin, tamsulosin hydrochloride and other alpha-blockers; if the chronic prostatitis, more need to follow the doctor’s instructions to apply alpha-blockers such as tamsulosin. 2. Urethritis: If it is gonorrhea urethritis, patients need to follow the doctor’s instructions oral ceftriaxone, macrolide, ampicillin and other antibiotics; if it is non-gonococcal urethritis, need to follow the doctor’s instructions oral roxithromycin, azithromycin, ofloxacin, enoxacin and other antibiotics. 3. prostate abscess: for prostate abscess, patients need to follow the doctor’s prescription oral metronidazole, at the same time need to cooperate with the doctor through the intravenous drip application of benzylpenicillin, clindamycin and other antibiotics. The above drugs should be used under the guidance of the doctor. Perineal pain may also be caused by other factors, it is recommended that patients go to the regular hospital in time for treatment. To summarize, patients with perineal pain caused by the prostate gland need to go to the hospital in time. Cooperate with the doctor to actively treat the original disease.