Poor coagulation does not usually heal on its own and requires treatment. Congenital poor coagulation is incurable but can relieve symptoms, and acquired poor coagulation is partially curable. Poor coagulation is divided into two types: congenital and acquired. Congenital coagulation abnormalities mainly include hemophilia, hereditary FⅪ deficiency, and combined FⅤ and FⅦ deficiency. As it is a hereditary disease caused by genetic defects, congenital coagulation abnormality cannot be cured. It is important to avoid strenuous activities in daily life, avoid bumps and bruises, and supplement coagulation factors in time for replacement therapy when bleeding occurs. Acquired coagulation abnormalities mainly include vitamin K deficiency and liver disease. Vitamin K deficiency requires attention to a balanced daily diet and timely supplementation of vitamin K. Symptoms can be relieved or even cured. Poor coagulation function caused by liver disease needs to control the primary disease, the primary disease of liver disease is controlled, generally the coagulation function can be restored. Poor coagulation function should identify the specific causes and follow the doctor’s instructions to standardize the treatment.