Some patients develop fibrous nodules that form localized lumps after lipofilling. The causes of fibrous nodules are numerous, which may be caused by uneven injection of fat particles resulting in excessive distribution in the local area and inactivation after being wrapped by the body fibers; it may also be due to the one-time injection of too much fat, resulting in the injection of the central fat does not get adequate blood supply and nutritional supplementation, coupled with their own slow metabolism, the emergence of fat clustering, which will lead to the formation of the phenomenon of hard nodules after autologous lipofilling; and also in the post-operation period Failure to carry out timely pressure bandage and massage physiotherapy can also lead to calcification and necrosis of fat particles. Therefore, standardized and reasonable operation must be carried out during and after the operation to avoid the appearance of fibrous nodules. For patients with mild symptoms, the fibers can be absorbed by the body without treatment; for patients with severe symptoms, the fibers can be extracted out of the body by negative pressure suction.