Prostate cancer is mainly caused by genetic mutations in the cells. There are many reasons why cells undergo genetic mutations, and genetics, overweight, and smoking are highly correlated with prostate cancer. First, genetic mutations are hereditary. Prostate cancer can occur in men with specific genetic mutations, for example, in some families with breast and ovarian cancer, and prostate cancer may be at higher risk in these families. Some genes do not directly cause cancer, but may make the cells more susceptible to extracellular carcinogens (oncogens). This is another factor in the development of prostate cancer caused by genetic mutations. Second, the risk of prostate cancer is higher in people who eat high-fat foods and red meat and lack the necessary physical activity that leads to an overweight body. This is mainly due to the fact that some substances necessary for the synthesis of sex hormones gather in large quantities in this group of people, resulting in higher levels of sex hormones, which can increase the risk of developing prostate cancer. Thirdly, smokers have a higher risk of prostate cancer, mainly because some chemicals in cigarettes have a significant cancer-promoting effect and cause prostate cancer. Usually the prognosis of prostate cancer due to this factor is poor. Fourth, diet may be a key factor in prostate cancer. Studies have shown a link between a diet high in saturated fat and prostate cancer. Lack of fruit and vegetable intake is the main reason why people on a high fat diet will be more prone to develop not only malignant diseases such as bowel cancer but also prostate cancer because they do not eat enough vegetables. In addition to a high fat diet, a very high calcium intake is also associated with prostate cancer. A relatively rare condition is that some people have cancer in their body itself, which metastasizes or spreads directly to the prostate through blood or lymph, which is also a cause of prostate cancer, and this condition belongs to the prostate metastasis of cancer.