Poor ovarian function and premature aging performance Patients with poor ovarian function and premature aging often have a rise in gonadotropin levels and a decline in estrogen, accompanied by varying degrees of hot flashes and excessive sweating, vaginal dryness, decreased libido and other pre and post-menopausal symptoms, so that the patient is aging before she gets old, causing great pain to her physical and mental health and couple’s life, affecting the quality of life of women. Usually, if a young woman with poor premature ovarian failure still has a chance to recover part of her function through comprehensive conditioning, she will have a great hope of doing IVF. For more serious premature failure patients with very few egg reserves, the hope of doing IVF is also very small. Premature ovarian failure is defined as persistent amenorrhea and atrophy of the sex organs before the age of 40 in women who have established regular menstruation, often with a rise in gonadotropin levels and a fall in estrogen. Its incidence accounts for 1% to 3% of adult women and has been on the rise in recent years. Patients often exhibit menstrual disorders or progressive menstrual sporadicity, followed by amenorrhea, and are accompanied by pre and postmenopausal symptoms such as hot flashes and excessive sweating, dry skin, vaginal dryness, and decreased libido to varying degrees. The ovary is the most important female reproductive organ and the main reproductive endocrine gland. It has two main functions, one is the reproductive function, i.e. generating mature follicles and ovulation; the other is the function of secreting sex hormones (estrogen, progesterone, androgen, etc.), which are involved in the regulation of the body’s physiological functions, maintaining the balance of the secretion system, and maintaining the female sex characteristics and body image. Ovarian failure firstly affects women’s reproductive physiological functions, resulting in their inability to produce and discharge qualified and mature eggs, thus affecting pregnancy; secondly, it may have certain effects on women’s physique, skin, hair and even voice, etc., as well as the appearance of different degrees of menopausal syndromes. At present, the exact cause of premature ovarian failure is not very clear, but more certain chromosomal abnormalities, autoimmune diseases, infections, taking certain drugs, surgery, viral infections, radiotherapy and other factors, other reasons are life stress, mental tension, bad habits and environmental pollution. Menstrual disorders should find the cause of the disease as early as possible. So far, there is no clear and effective treatment that can restore ovarian function. The key to treating premature ovarian failure is early detection and treatment. Once a woman finds that her menstrual flow decreases or suddenly stops, she should go to the hospital in time and should not delay and miss the best time for treatment. The treatment of premature ovarian failure should be based on the patient’s specific situation, such as age, cause of the disease, whether there is a requirement for childbearing, the presence of developing follicles in the ovaries and economic status, etc. to determine the treatment plan. How to Treat Poor Ovarian Function and Premature Failure The most commonly used treatment for premature ovarian failure is estrogen-progestin artificial cycle therapy. This treatment can not only relieve the symptoms of unstable vasodilation and contraction caused by the reduction of estrogen, but also prevent atrophy of sex organs, osteoporosis and cardiovascular diseases caused by lipid metabolism disorders. However, long-term use of the drug should be wary of liver function damage, thrombosis and increased risk of breast cancer and endometrial cancer, so it should be used under medical supervision. For women with reproductive requirements, estrogen-progestin artificial cycle treatment can be used for 3 to 5 months to monitor ovulation and guide sexual life, and assisted reproductive technology can be used to help patients achieve fertility if necessary. After the age of 30, the ovaries will enter a period of decline, and attention should be paid to actively protect the ovaries. Premature ovarian failure is the root cause of a series of changes in the body, which is fundamental for women to maintain their youth and beauty. IVF First Sweetheart reminds you that if you have scanty menstrual flow, menstrual cycle disorders, and occasional symptoms of afternoon low-grade fever for no apparent reason, you need to talk to your gynecologist in a timely manner. Women who are preparing to have children and undergoing IVF need to have blood tests for endocrine hormones (estrogen, progesterone, androgens, anti-mullerian tube hormone, etc.) to assess the function of the ovaries, and pelvic ultrasound (uterine morphology, thickness of the endometrium, size of the ovaries, and follicular basal number) to predict the ovarian reserve, which is an important basis for the Assisted Reproduction Center to assess the success rate of your IVF.