The symptoms of lung cancer patients are not only cough, hemoptysis, chest tightness and shortness of breath, but also endocrine disorders. What kinds of endocrine disorders are there? (1) Pro-adrenocorticotropic hormone score, leading to Cushing’s syndrome. Small cell lung cancer or bronchial carcinoid tumor is the most common cell type causing Cushing’s syndrome. It manifests as full moon face, buffalo back, etc. ② Secretion of parathyroid hormone, leading to hypercalcemia and hypophosphatemia. Commonly seen in squamous carcinoma. Patients present with drowsiness, anorexia, nausea, vomiting and weight loss and mental changes. Calcium levels may return to normal after removal of the tumor. (iii) Secretion of gonadotropins: gynecomastia, often with hypertrophic osteoarthropathy. There are few lung cancers with combined ectopic gonadotropins, and most of them are large cell lung cancers. ④Secretion of antidiuretic hormone: Inappropriate secretion of antidiuretic hormone can cause anorexia, nausea, vomiting and other symptoms of water intoxication, and can also be accompanied by progressively worsening neurological complications. It is characterized by hyponatremia (serum sodium <135 mmol/L) and hypotonicity (plasma osmolality <280 mOsm/kg). ⑤ Insulin is secreted, leading to hypoglycemia. It is seen in squamous carcinoma and can be reduced after removal of the tumor. (6) Carcinoid syndrome: The typical features of carcinoid syndrome are abnormal skin, cardiovascular, gastrointestinal and respiratory functions. The main manifestations are flushing or edema of the face and upper trunk, increased gastrointestinal motility, diarrhea, tachycardia, wheezing, pruritus and abnormal sensation. These paroxysmal signs and symptoms are associated with the release of different vasoactive substances by the tumor, including bradykinin, vasopressin and catecholamines in addition to 5-hydroxytryptamine.