A, mycoplasma and male infertility 1, mycoplasma has been one of the very common factors leading to male infertility. Mycoplasma is widely distributed in nature. In addition to people, many animals such as cats, cattle, chickens, dogs, ducks, sheep, horses, rats, monkeys, pigs, pigeons, etc., as well as insects and plants are able to carry and store this pathogen. Mycoplasma is a class of prokaryotic microorganisms, between bacteria and viruses in size. There are three types of mycoplasma pathogenic to humans, among which Mycoplasma solium is a common pathogen of the human genitourinary tract and is associated with many genitourinary tract infections, perinatal infections and infertility, and is one of the pathogens of sexually transmitted diseases. The rate of isolation of human mycoplasma in the genital tract of infants before 1 year of age is 4%; for male infants, it is 6% and for female infants, 38%. Mycoplasma in the genital tract decreases rapidly with age. Mycoplasma can rarely be isolated from the genitourinary tract in adolescent boys, while the isolation rate of Mycoplasma decidua in girls is 27% and that of Mycoplasma humana is 5%. However, after puberty, the rate of isolation of mycoplasma from the genital tract will gradually increase, and it will be more significant after sexual intercourse. The actual fact is that you can find a lot of people who are not able to get a good deal on a lot of things. The actual fact is that you can find a lot of people who are not able to get a good deal on a lot of things. Mycoplasma also continues to infect the seminal tract, seminal vesicles and testicles, affecting the quality of sperm and semen and causing infertility. 4, mycoplasma interference with sperm movement: sperm movement is an important function of healthy sperm, mycoplasma infection of sperm, often attached to the head and tail of the sperm, so that the entire sperm hung with the size of the attachment, resulting in sperm swimming weak, entangled with each other, resulting in infertility; mycoplasma increase in sperm deformity: mycoplasma infection leads to an increase in sperm deformity is another feature of infertility. According to clinical observation, the sperm deformity rate can sometimes be as high as 80% in such infertility patients; mycoplasma destroys spermatogenic cells: there are a large number of spermatogenic cells in the varicocele of the testis, and these spermatogenic cells develop and reproduce to form sperm. When mycoplasma enters the testicular varicose ducts from the urethra and prostate, it destroys the spermatogenic cells, causing the “spermatogenic factory” to produce shoddy products, leading to infertility. In recent years, a large amount of literature has confirmed that mycoplasma is a microorganism parasitic in the genitourinary tract, especially in the female genital tract, where the temperature and humidity are suitable and is an important place for mycoplasma to live. Infertility can be caused by mycoplasma infections in women of reproductive age. Mycoplasma infection is one of the factors causing infertility, and even if conception occurs, it is likely to cause stillbirth, miscarriage or intrauterine fetal infection. Therefore, mycoplasma testing should become a routine for infertile couples. If the female partner has not turned negative after a course of treatment, the male partner should be tested for mycoplasma in order to cut off the source of infection early and better coordinate with other measures to treat infertility. The main mechanism of female infertility caused by mycoplasma: is to cause chronic inflammation of the endometrium. In addition, mycoplasma can also break down the mucosa and release prostaglandins, causing contraction of the uterus, cleavage of fertilized eggs, shedding and infertility. These infection induced metaplasia and autoimmunity may also be factors of infertility. Third, treatment Generally, tetracycline, doxycycline and erythromycin are used for treatment, but there have been many strains of bacteria that have become resistant to the new generation of quinolones, such as fluazinic acid and ciprofluoperazine, in addition to azithromycin, etc. are also very effective against Mycoplasma solani infection. In addition, Azithromycin is also effective against Mycoplasma solani infection. According to Chinese medicine, Mycoplasma solani infection is the evil of dampness and heat. The two men and women should be treated at the same time, and avoid direct contact as much as possible before the cure, and use condoms during sex, otherwise it will cause mutual infection between men and women due to sexual life, repeated infection and delayed healing. 2, regular review. Can not be subjective symptoms as the criteria for discontinuing drugs, but should depend on the objective examination results, in the treatment process to timely, multiple re-examinations, more than 3 consecutive negative test results before discontinuing drugs, if incorrect discontinuation of drugs, the pathogens will produce drug resistance, increasing the difficulty of treatment. 3, life and living pay attention to hygiene, especially with the pubic contact objects should be strictly clean, try not to go to the sauna, swimming pools and other public places. 4, keep a happy mood, optimistic and positive attitude towards the disease.